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首页 > 产品中心 > Anti-Dicer Rabbit pAb
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Anti-Dicer Rabbit pAb

货号:GB11410

品牌:
目标价:¥500 促销价:
  • IHC、IF
  • H,Rat,M
  • 1:1000
订购规格:
  • 100ul
订购数量:

Product Information


Description

Dicer rabbit polyclonal

Protein full nameEndoribonuclease Dicer

Synonyms

DICER1, DCR1, Dicer, Dicer1e, HERNA, MNG1, RMSE2, K12H4.8-LIKE, dicer 1, ribonuclease III
ImmunogenKLH conjugated Synthetic peptide corresponding to Mouse Dicer
IsotypeIgG
PurityAffinity purification
Subcellular location

Cytoplasm

Uniprot IDQ9UPY3,Q8R418





Applications


Applications

IHC,IF



SpeciesHuman,Mouse,Rat

Dilution1:1000

Positive tissue

brain,kidney







Background


        Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation.       

     



Images


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Immunohistochemistry analysis of paraffin-embedded rat brain using Dicer (GB11410) at dilution of 1:1000

 



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Immunohistochemistry analysis of paraffin-embedded human kidney using Dicer (GB11410) at dilution of 1:1000

 




Storage


StorageStore at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage BufferPBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 




NOTE: This product is intended for research only.




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