ATF2 rabbit polyclonal
|Protein full name|
Cyclic AMP-dependent transcription factor ATF-2
ATF2, CRE-BP1, CREB-2, CREB2, HB16, TREB7, activating transcription factor 2
KLH conjugated Synthetic peptide corresponding to Mouse ATF2
A transcription factor that is a member of the leucine zipper family of DNA binding proteins. The protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation .
Western blot analysis of ATF2(GB11315-2) at dilution of 1:600.
Lane 1:PC12cell lysate
Lane 2:Mouse cerebellum tissue lysate
Lane 3:Mouse brain tissue lysate
Lane 4:Rat brain tissue lysate
Lane 5:Rat cerebral infarction tissue lysate
|Storage||Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.|
|Storage Buffer||PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.|
NOTE: This product is intended for research only.