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首页 > 产品中心 > Anti-ATF2 Rabbit pAb
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Anti-ATF2 Rabbit pAb

货号:GB11315-2

品牌:
目标价:¥500 促销价:
  • WB
  • Rat,M
  • 1:500-1:1000
订购规格:
  • 100ul
订购数量:

Product Information


Description

ATF2 rabbit polyclonal

Protein full name

Cyclic AMP-dependent transcription factor ATF-2

Synonyms

ATF2, CRE-BP1, CREB-2, CREB2, HB16, TREB7, activating transcription factor 2

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse ATF2

IsotypeIgG
PurityAffinity purification

Predicted MW.

52 kDa

Observed MW.

52 kDa

Uniprot IDP15336,P16951,Q00969





Applications


ApplicationsWB
Species

Human,Mouse,Rat

Dilution

1:500-1:1000

Positive tissue

PC12,brain





Background


        A transcription factor that is a member of the leucine zipper family of DNA binding proteins. The protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation .

    



Images


blob.png

Western blot analysis of ATF2(GB11315-2) at dilution of 1:600.

Lane 1:PC12cell lysate

Lane 2:Mouse cerebellum tissue lysate

Lane 3:Mouse brain tissue lysate

Lane 4:Rat brain tissue lysate

Lane 5:Rat cerebral infarction tissue lysate




Storage


StorageStore at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage BufferPBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 




NOTE: This product is intended for research only.




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