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Anti -RAPGEF5 Rabbit pAb

货号:GB111597

品牌:Servicebio

价格:¥650

规格: 100 μl

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Product Information

 

Description RAPGEF5 rabbit polyclonal
Protein full name Rap guanine nucleotide exchange factor 5
Synonyms Guanine nucleotide exchange factor for Rap1, M-Ras-regulated Rap GEF, Rapgef5, Mrgef, Kiaa0277, Gfr, Related to Epac, Rap guanine nucleotide exchange factor 5
Immunogen KLH conjugated Synthetic peptide
corresponding to Mouse RAPGEF5
Isotype IgG
Purity Affinity purification
Subcellular location Nucleus
Uniprot ID Q8C0Q9, P83900

 


 

Applications

 

Applications Species Dilution Positive Tissue
IHC Mouse, Rat 1: 700-1: 1400 ovary, brain, liver, spleen

 


 

Background
 

Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as Repac, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation. 

 


 

Images

 


Immunohistochemistry analysis of paraffin-embedded mouse ovary using RAPGEF5 (GB111597) at dilution of 1: 1400
 

Immunohistochemistry analysis of paraffin-embedded rat ovary using RAPGEF5 (GB111597) at dilution of 1: 1400
 

Immunohistochemistry analysis of paraffin-embedded mouse brain using RAPGEF5 (GB111597) at dilution of 1: 1400
 

Immunohistochemistry analysis of paraffin-embedded mouse liver using RAPGEF5 (GB111597) at dilution of 1: 1400
 

Immunohistochemistry analysis of paraffin-embedded rat spleen using RAPGEF5 (GB111597) at dilution of 1: 1400
 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
 

 

NOTE: This product is intended for research only.