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Anti -SCN4B Rabbit pAb

货号:GB111596

品牌:Servicebio

价格:¥650

规格: 100 μl

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Product Information

 

Description SCN4B rabbit polyclonal
Protein full name Sodium channel subunit beta-4
Synonyms Scn4b, Gm1471, sodium channel, voltage gated, type IV beta subunit, voltage-gated, LQT10, Navbeta4, ATFB17
Immunogen Recombinant protein corresponding to
Mouse SCN4B
Isotype IgG
Purity Affinity purification
Subcellular location Plasma membrane
Uniprot ID Q7M729, Q7M730

 


 

Applications

 

Applications Species Dilution Positive Tissue
IHC Mouse, Rat 1: 1000-1: 2000 brain, heart

 


 

Background
 

The SCN4B protein modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom.The protein has been found to be expressed at a high level in dorsal root ganglia, at a lower level in brain, spinal cord, skeletal muscle and heart. 

 


 

Images

 


Immunohistochemistry analysis of paraffin-embedded mouse brain using SCN4B (GB111596) at dilution of 1: 2000
 

Immunohistochemistry analysis of paraffin-embedded rat heart using SCN4B (GB111596) at dilution of 1: 2000
 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
 

 

NOTE: This product is intended for research only.