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Anti -PDE10A Rabbit pAb

货号:GB111420

品牌:Servicebio

价格:¥650

规格: 100 μl

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Product Information

 

Description PDE10A rabbit polyclonal
Protein full name cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Synonyms Pde10a, 5''-cyclic phosphodiesterase 10A, cAMP and cAMP-inhibited cGMP 3'', FLJ11894, Phosphodiesterase 10A, Phosphodiesterase 10A1
Immunogen Recombinant protein corresponding to
Mouse PDE10A
Isotype IgG
Purity Affinity purification
Predicted MW. 89 kDa
Observed MW. 75 kDa
Uniprot ID Q8CA95, Q9QYJ6

 


 

Applications

 

Applications Species Dilution Positive Tissue
WB Mouse, Rat 1: 500-1: 1000 brain, testis

 


 

Background

 

The PDE10A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides,eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.

     


 

Images

 



Western blot analysis of PDE10A (GB111420) at dilution of 1: 1000
Lane 1: Mouse brain tissue lysate
Lane 2: Mouse testis tissue lysate
Lane 3: Rat brain tissue lysate
Lane 4: Rat testis tissue lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.