|Description||PDE10A rabbit polyclonal|
|Protein full name||cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A|
|Synonyms||Pde10a, 5''-cyclic phosphodiesterase 10A, cAMP and cAMP-inhibited cGMP 3'', FLJ11894, Phosphodiesterase 10A, Phosphodiesterase 10A1|
|Immunogen||Recombinant protein corresponding to
|Predicted MW.||89 kDa|
|Observed MW.||75 kDa|
|Uniprot ID||Q8CA95, Q9QYJ6|
|WB||Mouse, Rat||1: 500-1: 1000||brain, testis|
The PDE10A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides，eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.
|Storage||Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.|
|Storage Buffer||PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.|
NOTE: This product is intended for research only.