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Anti -Ephrin B1 Rabbit pAb

货号:GB111417

品牌:Servicebio

价格:¥ 650

规格: 100 μl

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Product Information

 

Description Ephrin B1 rabbit polyclonal
Protein full name Ephrin-B1
Synonyms EFL-3, ELK-L, EPH-related receptor tyrosine kinase ligand 2, LERK-2, EFNB1, EFL3, EPLG2, LERK2
Immunogen Recombinant protein corresponding to
Mouse Ephrin B1
Isotype IgG
Purity Affinity purification
Predicted MW. 38 kDa
Observed MW. 45 kDa
Uniprot ID P98172

 


 

Applications

 

Applications Species Dilution Positive Tissue
WB Human 1: 500-1: 1000 PC3, Hacat, HepG2

 


 

Background

 

Ephrin-B1, also known as LERK-2, ELK-L, EFL-3, Cek5-L, and STRA-1 , is a member of the ephrin ligand family which binds members of the Eph receptor family. Several signaling molecules have been shown to interact with the cytoplasmic region, although specific signaling roles have yet to be elucidated. Ephrin-B1 has been shown to bind EphA3, EphB1, EphB2, EphB3, and EphB4. The extracellular domains of human and mouse Ephrin-B1 share 94% amino acid identity. Only membrane-bound or Fc-clustered ligands are capable of activating the receptor in vitro. Soluble monomeric ligands bind the receptor but do not induce receptor autophosphorylation and activation. In vivo, the ligands and receptors display reciprocal expression. It has been found that nearly all receptors and ligands are expressed in developing and adult neural tissue. The Eph/ephrin families also appear to play a role in angiogenesis.

     


 

Images

 



Western blot analysis of Ephrin B1 (GB111417) at dilution of 1: 1000
Lane 1: PC3 cell lysate
Lane 2: Hacat cell lysate
Lane 3: HepG2 cell lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.