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Anti -GCP4 Rabbit pAb

货号:GB111447

品牌:Servicebio

价格: ¥650

规格: 100 μl

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Product Information

 

Description GCP4 rabbit polyclonal
Protein full name Gamma-tubulin complex component 4
Synonyms GCP-4, hGCP4, Gamma-ring complex protein 76 kDa, h76p, hGrip76, TUBGCP4, 76P, GCP4
Immunogen KLH conjugated Synthetic peptide
corresponding to Mouse GCP4
Isotype IgG
Purity Affinity purification
Predicted MW. 76 kDa
Observed MW. 76 kDa
Uniprot ID Q9UGJ1

 


 

Applications

 

Applications Species Dilution Positive Tissue
WB Humant 1: 500-1: 800 MCF7, HepG2, HCT116

 


 

Background

 

This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy.

 


 

Images

Western blot analysis of GCP4 (GB111447)
at dilution of 1: 800
Lane 1: MCF7 cell lysate
Lane 2: HepG2 cell lysate
Lane 3: HCT116 cell lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.