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Anti -CXCL16 Rabbit pAb

货号:GB111441

品牌:Servicebio

价格:¥ 650

规格: 100 μl

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Product Information

 

Description CXCL16 rabbit polyclonal
Protein full name C-X-C motif chemokine 16
Synonyms Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, Srpsox,  SR-PSOX, Small-inducible cytokine B16, Transmembrane chemokine CXCL16, Cxcl16
Immunogen Recombinant protein corresponding to
Mouse CXCL16
Isotype IgG
Purity Affinity purification
Predicted MW. 27 kDa
Observed MW. 28-35 kDa
Uniprot ID Q8BSU2, Q6AXU5

 


 

Applications

 

Applications Species Dilution Positive Tissue
WB Mouse, Rat 1: 500-1: 1000 lung, lymph node, stomach

 


 

Background

 

CXCL16 belongs to the CXC chemokine family, which is synthesised in plasmacytoid dendritic cell as a transmembrane molecule. It exists in a transmembrane and soluble form. The transmembrane form of CXCL16 functions as an adhesion molecule for CXCR6-expressing cells, whereas the soluble form of CXCL16 mediates infiltration of circulating cells into sites of injury. CXCL16, has been proposed as an important pathogenic mediator in inflammatory diseases, including rheumatoid arthritis, glomerulonephritis, or prostate cancer. CXCL16 has been implicated in some forms of renal disease such as lupus nephritis and antiglomerular basement membrane nephritis. CXCL16 also plays a pivotal role in the pathogenesis of angiotensin II–induced renal injury and fibrosis through regulation of macrophage and T cell infiltration and bone marrow–derived fibroblast accumulation.

 


 

Images

 

Western blot analysis of CXCL16 (GB111441)
at dilution of 1: 1000
Lane 1: Mouse lung tissue lysate
Lane 2: Mouse lymph node tissue lysate
Lane 3: Mouse stomach tissue lysate
Lane 4: Rat lung tissue lysate
Lane 5: Rat lymph node tissue lysate
Lane 6: Rat stomach tissue lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.