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Anti -HES5 Rabbit pAb

货号:GB111398

品牌:Servicebio

价格:¥650

规格: 100 μl

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Product Information

 

 

Description

HES5 rabbit polyclonal

Protein full name Transcription factor HES-5

Synonyms

Hairy and enhancer of split 5, Hes5, bHLHb38, Class B basic helix-loop-helix protein 38, Hairy and enhancer of split 5, hes family bHLH transcription factor 5

Immunogen Recombinant protein corresponding to
Mouse HES5
Isotype IgG
Purity Affinity purification
Predicted MW. 18 kDa
Observed MW. 18 kDa
Uniprot ID P70120, Q03062

 

 


 

Applications

 

 

Applications WB
Species Mouse, Rat
Dilution 1: 500-1: 1000
Positive Tissue kidney, liver, brain,
fetal mouse

 


 

Background

Hairy and Enhancer-of-split homologues 5 (HES5) is a helix-loop-helix transcriptional factor that negatively regulates cell differentiation during embryogenesis. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. HES5 as a transcriptional repressor of genes that require a bHLH protein for their transcription and plays an important role as neurogenesis negative regulator.  HES5 is reported to be a down stream effector of the Notch Signaling Pathway and is expressed in advanced ovarian serous adenocarcinomas as well as in cervical squamous carcinoma.


 

Images

 

Western blot analysis of HES5 (GB111398)
at dilution of 1: 1000
Lane 1: Mouse kidney tissue lysate
Lane 2: Mouse liver tissue lysate
Lane 3: Mouse brain tissue lysate
Lane 4: Fetal mouse lysate
Lane 5: Rat kidney tissue lysate
Lane 6: Rat liver tissue lysate
Lane 7: Rat brain tissue lysate


 

 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.