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Anti -HMGA2 Rabbit pAb

货号:GB111395

品牌:Servicebio

价格:¥650

规格: 100 μl

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Product Information

 

 

Description

HMGA2 rabbit polyclonal

Protein full name High mobility group protein HMGI-C

Synonyms

High mobility group AT-hook protein 2, LIPO, Hmga2, Hmgic, BABL, STQTL9

Immunogen Recombinant protein corresponding to
Mouse HMGA2
Isotype IgG
Purity Affinity purification
Subcellular location Nucleus
Uniprot ID P52927, O88791

 


 

Applications

 

 

Applications IHC,IF
Species Mouse, Rat,Mouse, Rat
Dilution 1: 1400-1: 2800,1: 1400-1: 2800
Positive Tissue liver, spleen, kidney, placenta, colon, brain,brain, heart, testis, stomach

 


 

Background

HMGA2 belongs to the family of high mobility group with AT-hook DNA binding domain. HMGA proteins are considered architectural transcription factors; they do not have direct transcriptional activation capacity, but instead regulate gene expression by changing DNA conformation through binding to AT-rich regions in the DNA and/or direct interaction with other transcription factors . HMGA2 is abundantly and ubiquitously expressed and plays a crucial role during embryonic development. HMGA2 promotes stem cell self-renewal and research studies have shown that decreased HMGA2 expression is associated with stem cell aging. Investigators have shown that expression levels of HMGA2 are very low in normal adult tissues, while either overexpression or rearrangement is associated with many types of cancer.
 


 

Images

 

Immunohistochemistry analysis of paraffin-embedded mouse liver using
HMGA2 (GB111395) at dilution of 1: 1400


 

Immunohistochemistry analysis of paraffin-embedded mouse spleen using
HMGA2 (GB111395) at dilution of 1: 1400
 

Immunohistochemistry analysis of paraffin-embedded mouse kidney using
HMGA2 (GB111395) at dilution of 1: 1400
 

Immunohistochemistry analysis of paraffin-embedded mouse placenta using
HMGA2 (GB111395) at dilution of 1: 1400
 

Immunohistochemistry analysis of paraffin-embedded rat colon using
HMGA2 (GB111395) at dilution of 1: 1400
 

Immunohistochemistry analysis of paraffin-embedded rat brain using
HMGA2 (GB111395) at dilution of 1: 1400
 


Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using
HMGA2 (GB111395) at dilution of 1: 1400
 

Immunofluorescent analysis of paraformaldehyde-fixed mouse heart using
HMGA2 (GB111395) at dilution of 1: 1400
 

Immunofluorescent analysis of paraformaldehyde-fixed mouse testis using
HMGA2 (GB111395) at dilution of 1: 1400
 

Immunofluorescent analysis of paraformaldehyde-fixed rat stomach using
HMGA2 (GB111395) at dilution of 1: 1400
 

 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.