Product Information
| Description |
BET3 rabbit polyclonal |
| Protein full name | Trafficking protein particle complex subunit 3 |
|
Synonyms |
BET3 homolog, Trappc3, Bet3, AU019197, AI835942, 1110058K12Rik, Yeast homolog of BET3, Trafficking protein particle complex subunit 3 |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse BET3 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW | 20 kDa |
| Observed MW. | 20 kDa |
| Uniprot ID | O43617, O55013, Q5U1Z2 |
Applications
| Applications | IHC |
| Species | Human, Mouse, Rat |
| Dilution | 1: 500-1: 1000 |
| Positive Tissue | liver, kidney, brain |
Background
TRAPPC3 (trafficking protein particle complex 3, also known as Bet3) is a component of TRAPP, a complex involved in the tethering of transport vesicles to the cis-Golgi membrane. There are three TRAPP complexes identified in yeast with distinct roles: TRAPPI in ER-Golgi traffic, TRAPPII in intra-Golgi and endosome-Golgi traffic, and TRAPPIII in autophagy. Recently it has been proposed that at least two complexes exist in mammals. It has also been reported that TRAPPC3 is required for Rabin8 centrosome trafficking and ciliogenesis. Expressed ubiquitously, TRAPPC3 protein is present in both membrane-bound and cytosolic forms.
Images
|
|
Western blot analysis of BET3 (GB111393) at dilution of 1: 1000 Lane 1: PC3 cell lysate Lane 2: HT29 cell lysate Lane 3: PANC1 cell lysate Lane 4: Mouse liver tissue lysate Lane 5: Mouse kidney tissue lysate Lane 6: Mouse brain tissue lysate Lane 7: Rat liver tissue lysate Lane 8: Rat kidney tissue lysate Lane 9: Rat brain tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
