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Anti -Glutamine Synthetase Rabbit pAb

货号:GB111177

品牌:Servicebio

价格:¥650

规格: 100 μl

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Product Information

 

Description

Glutamine Synthetase rabbit polyclonal

Protein full name Glutamine synthetase
 

Synonyms

GLUL, cell proliferation-inducing protein 59, GLNA, GLNS, GLUL, Glutamate ammonia ligase, Glutamate decarboxylase, Glutamine synthetase, GS, PIG43, PIG59,Proliferation inducing protein 43

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Glutamine Synthetase

Isotype IgG
Purity Affinity purification

Predicted MW.

42 kDa

Observed MW.

45 kDa

Uniprot ID

P15105, P09606

 


 

Applications

 

Applications

WB

Species

Mouse, Rat

Dilution

1: 500-1: 1500

Positive tissue

lung, brain

 


 

Background

 

Glutamine Synthetase catalyzes the conversion of ammonia and glutamate to glutamine. The function of Glutamine Synthetase is the detoxification of brain ammonia. It also has an important role in the metabolic regulation of neurotransmitter glutamate. Because of the multiple functions and importance of Glutamine Synthetase in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of Glutamine Synthetase is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation. The level of expression of Glutamine Synthetase is increased during ischemia in vivo or hypoxia in culture.
 


 

Images

 

Western blot analysis of Glutamine Synthetase (GB111177) at dilution of 1: 1000
Lane 1: NIH/3T3 cell lysate
Lane 2: PC12 cell lysate
Lane 3: Mouse lung tissue lysate
Lane 4: Mouse brain tissue lysate
Lane 5: Rat lung tissue lysate
Lane 6: Rat brain tissue lysate
 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.