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Anti -MEF2C Rabbit pAb

货号:GB111249

品牌:Servicebio

价格:¥650

规格: 100μl

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Product Information

 

Description

MEF2C rabbit polyclonal

Protein full name
Myocyte-specific enhancer factor 2C
 

Synonyms

Myocyte enhancer factor 2C, Mef2c, MADS box transcription enhancer factor 2 polypeptide C, Myocyte enhancer factor 2C

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse MEF2C

Isotype IgG
Purity Affinity purification

Predicted MW.

51 kDa

Observed MW.

51/47 kDa

Uniprot ID

Q8CFN5

 


 

Applications

 

Applications

WB

Species

Mouse

Dilution

1: 500-1: 1000

Positive tissue

brain, spleen,lymph nodes

 


 

Background

 

The MEF2C belongs to the MEF2 family. It is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. It is crucial for normal neuronal development, distribution, and electrical activity in the neocortex and is necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. This protein is required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells.


 

Images

 

Western blot analysis of MEF2C (GB111249) at dilution of 1: 1000
Lane 1: Mouse brain tissue lysate
Lane 2: Mouse spleen tissue lysate
Lane 3: Mouse lymph nodes tissue lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.