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Anti -HSF1 Rabbit pAb

货号:GB11932

品牌:Servicebio

价格:¥500

规格: 100 μl

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Product Information

 

Description HSF1 rabbit polyclonal
Protein full name

Heat shock factor protein 1

Synonyms

Hsf1, HSF1, HSTF1, heat shock transcription factor 1

Immunogen

Recombinant protein corresponding to Mouse HSF1

Isotype IgG
Purity Affinity purification
Subcellular location

Cytoplasm, Nucleus

Uniprot ID

Q00613, P38532

 


 

Applications

 

Applications

IHC

IF

Species

Human, Mouse, Rat

Human, Mouse, Rat

Dilution

1: 500-1: 1500

1: 250-1: 500

Positive tissue

lung cancer, testis

lung cancer, testis

 


 

Background

 

The HSF1 protein regulates the heat shock response (HSR) pathway in humans by acting as the major transcription factor for heat shock proteins. The HSR plays a protective role by ensuring proper folding and distribution of proteins within cells. This pathway is induced by not only temperature stress, but also by a variety of other stressors such as hypoxic conditions and exposure to contaminants. HSF1 transactivates genes for many cytoprotective proteins involved in heat shock, DNA damage repair, and metabolism. This illustrates the versatile role of HSF1 in not only the heat shock response, but also in aging and diseases. 
 


 

Images

 

Immunohistochemistry analysis of paraffin-embedded human lung cancer using HSF1 (GB11932) at dilution of 1: 1000
 

 

   

Immunohistochemistry analysis of paraffin-embedded mouse testis using HSF1 (GB11932) at dilution of 1: 1000

   

 

​Immunohistochemistry analysis of paraffin-embedded rat testis using HSF1 (GB11932) at dilution of 1: 1000

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.