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Anti -Junctional Adhesion Molecule 1/JAM-A Rabbit pAb

货号:GB111062

品牌:Servicebio

价格:¥650

规格: 100μl

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Product Information

 

Description

JAM-A rabbit polyclonal

Protein full name

Junctional adhesion molecule A

Synonyms

JAM-A, Junctional adhesion molecule 1, JAM-1, CD321, F11r, Jam1, Jcam, Jcam1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse JAM-A

Isotype IgG
Purity Affinity purification

Predicted MW.

32 kDa

Observed MW.

32-41 kDa

Uniprot ID

Q9Y624, O88792, Q9JHY1

 


 

Applications

 

Applications

WB

Species

Human, Mouse, Rat

Dilution

1: 500-1: 1000

Positive tissue

liver, colon, small intestine

 


 

Background

 

Seems to play a role in epithelial tight junction formation. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as a receptor for reovirus, a ligand for the integrin LFA1, involved in leukocyte transmigration, and a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

 


 

Images

 

Western blot analysis of JAM-A (GB111062) at dilution of 1: 1000

Lane 1: Caco2 cell lysate
Lane 2: SW480 cell lysate
Lane 3: Mouse liver tissue lysate
Lane 4: Mouse colon tissue lysate
Lane 5: Rat liver tissue lysate
Lane 6: Rat small intestine tissue lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.