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Anti -Serum Response Factor SRF Rabbit pAb

货号:GB111048

品牌:Servicebio

价格:¥650

规格: 100μl

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Product Information

 

Description

SRF rabbit polyclonal

Protein full name

Serum response factor

Synonyms

c fos serum response element binding factor, SRF, ERP, MCM1, SAP2

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse SRF

Isotype IgG
Purity Affinity purification
Subcellular location

Nucleus

Uniprot ID

P11831Q9JM73D3ZHH8

 


 

Applications

 

Applications

IHC

IF

Species

Human, Mouse, Rat

Human, Mouse, Rat

Dilution

1: 1000-1: 2000

1: 500-1: 1000

Positive tissue

breast cancer, stomach, ovarian cancer, 

subcutaneous tumor, small intestine, heart, lung

breast cancer, stomach, ovarian cancer, 

subcutaneous tumor, small intestine, heart, lung

 


 

Background

 

This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).

 


 

Images

 

image.png

Immunohistochemistry analysis of paraffin-embedded human breast cancer using SRF (GB111048) at dilution of 1: 1500

   

image.png

Immunohistochemistry analysis of paraffin-embedded human stomach using SRF (GB111048) at dilution of 1: 1500

   

image.png

Immunohistochemistry analysis of paraffin-embedded human ovarian cancer using SRF (GB111048) at dilution of 1: 1500

   

image.png

Immunohistochemistry analysis of paraffin-embedded rat small intestine using SRF (GB111048) at dilution of 1: 1500

   

image.png

Immunohistochemistry analysis of paraffin-embedded mouse small intestine using SRF (GB111048) at dilution of 1: 1500

   

image.png

Immunohistochemistry analysis of paraffin-embedded mouse heart using SRF (GB111048) at dilution of 1: 1500

   

image.png

Immunohistochemistry analysis of paraffin-embedded mouse subcutaneous tumor using SRF (GB111048) at dilution of 1: 1500

   

image.png

Immunohistochemistry analysis of paraffin-embedded rat lung using SRF (GB111048) at dilution of 1: 2000

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.