ERK1 (pT202/pY204) + ERK2 (pT185/pY187) rabbit polyclona
|Protein full name||Mitogen-activated protein kinase 1|
|Synonyms||APK1, ERK, ERK-2, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK, mitogen-activated protein kinase 1|
|Immunogen||KLH conjugated Synthetic peptide corresponding to Mouse ERK2|
|Predicted MW.||42/44 kDa|
|Uniprot ID||P63085, Q63844|
lung, kidney, NIH/3T3
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Western blot analysis of Erk1 (pT202/pY204) + Erk2 (pT185/pY187) (GB11004) at dilution of 1:800.
Lane 1:Hela cell lysate
Lane 2:HUVEC cell lysate
Lane 3-5:NIH/3T3 cell lysate
Lane 6:Mouse lung tissue lysate
Lane 7:Mouse kidney tissue lysate
Lane 8:Rat lung tissue lysate
Lane 9:Rat kidney tissue lysate
|Storage||Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.|
|Storage Buffer||PBS with 0.02% sodium azide, 100μg/ml BSA and 50% glycerol.|
NOTE: This product is intended for research only.